Dermatology - Dermatology Video

Correct Answer - D The lines of Blaschko are defined by a pattern determined by nevoid representing non random lines on the human skin or mucosa. Blaschko lines or the lines of Blaschko are thought to represent pathways of epidermal cell migration and proliferation during the development of the fetus. Lines of Blaschko represent non-random developmental lines of the skin fundamentally differing from the system of dermatomes. They follow a'V' shape over the back, 'S' shaped whorls over the chest, stomach, and sides, and wary shapes on the head. The lines are belived to trace the migration of embryonic epidermal cells. The stripes are a type of genetic mosaicism. These lines characteristically do not follow the underlying nervous, Vascular, muscular or lymplatic structures in the skin. Lines of Blaschko are not ordinarily visibk, but are recognized in several cutaneous disorders that follow these arallel streaks. Ref: Syndromes: Rapid recognition and perioperative implications, by Bruno Bisonnette, Page 400; Neurocutaneous disorders: Phakomatosis and Hamartoneoplastic Syndromes, by Martino Ruggieri, Page 364.